Weight Cycling Increases Longevity Compared with Sustained Obesity in Mice
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چکیده
منابع مشابه
OBESITY AND WEIGHT CYCLING Use SAS® Software for Epidemiological Studies
Epidemic of obesity is a serious problem. According to CDC statistics for the United States population about 35.7% of adults and approximately 17% of children and adolescents (2-19 years old) were obese in 2009-2010. Numerous epidemiological studies demonstrated that obesity is a risk factor for multiple diseases like cancer and cardiovascular. The various weight loss and weight control program...
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BACKGROUND Obesity is associated with low-grade chronic inflammation attributed to dysregulated production, release of cytokines and adipokines and to dysregulated glucose-insulin homeostasis and dyslipidemia. Nutritional interventions such as dieting are often accompanied by repeated bouts of weight loss and regain, a phenomenon known as weight cycling (WC). METHODS In this work we studied t...
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Epigenetic changes can be induced by adverse environmental exposures, such as nutritional imbalance, but little is known about the nature or extent of these changes. Here we have explored the epigenomic effects of a sustained nutritional change, excess dietary methyl donors, by assessing genomic CpG methylation patterns in isogenic mice exposed for one or six generations. We find stochastic var...
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BACKGROUND Preeclampsia has been shown to be associated with obesity, with other risk factors for cardiovascular disease, and with subsequent cardiovascular disease itself. However, the possible association with weight gain and weight cycling has not been evaluated. METHODS In this prospective study of a cohort of 1644 pregnant women, we assessed adult weight change, intentional weight cyclin...
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ژورنال
عنوان ژورنال: Obesity
سال: 2018
ISSN: 1930-7381,1930-739X
DOI: 10.1002/oby.22290